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IGK Gene Clonality Assay (Gel)

Product information "IGK Gene Clonality Assay (Gel)"

This Research Use Only assay identifies immunoglobulin heavy chain clonality and is useful for the study of identifying clonal B-cell populations and evaluation of new research and methods in malignancy studies. This test kit includes three (3) master mixes. The IGK Tube A master mix targets the variable (V) and the joining (J) regions of the Ig kappa light chain locus. Whereas the IGK Tube B master mix targets kappa deleting element (Kde) rearrangements with the variable (V) region and the intragenic Jϰ-Cϰ region. The resulting Vϰ-Kde and Jϰ -Cϰ intron-Kde rearrangements are a result of unsuccessful rearrangements retained by the B-cell. The third master mix, the Specimen Control Size Ladder, targets multiple genes and generates a series of amplicons of approximately 100, 200, 300, 400, and 600 base pairs (bp) to ensure that the quality and quantity of input DNA is adequate to yield a valid result.
Product type: PCR Assay
Regulatory status: RUO
Platform: Gel Detection
Reactions: 33 rxns
Storage temperature: -70 °C
Shipping method: Dry ice
Country of distribution: Germany
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IGK Gene Clonality Assay (Gel)
€970.00* (Gel Detection (33 rxns))